ncRNA name | hsa-miR-223-3p |
ncRNA Category | miRNA |
Disease name | autoimmune uveitis |
Species | Homo sapiens |
Tissues/Cell_line | serum |
Methods | TaqMan OpenArray, qRT-PCR, flow cytometry |
Expression pattern | up-regulated |
Functional description | miR-223-3p is upregulated in animal models of uveitis and is able to drive inflammation via T cells and myeloid dendritic cells, two cell types that are implicated in the biology of uveitis.miR-223-3p has been suggested as a good candidate for miRNA targeting in the treatment of inflammatory diseases such as NIU. |
PubMed ID | 29435587 |
Year | 2018 |
Title | A Disease-Associated MicroRNA Cluster Links Inflammatory Pathways and an Altered Composition of Leukocyte Subsets to Noninfectious Uveitis. |
Drug-related ncRNA | NO |
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